Chlorthalidone (Hygroton) –
What You Should Know

Brand Name: Thalitone (Hygroton)

What is Chlorthalidone (Hygroton)?

The Information about Chlorthalidone (Hygroton) contained herein is a compilation of materials available from and simplified for the average consumer.

chlorthalidone saltChlorthalidone, also known by the brand name Hygroton is a diuretic that helps rid your body of salt (sodium) and water. Chlorthalidone (Hygroton) works by making your kidneys put more sodium into your urine. The sodium, in turn, takes water with it from your blood. That decreases the amount of fluid flowing through your blood vessels, which reduces pressure on the walls of your arteries.

There are drug free alternatives to lowering your blood pressure that may be effective for you. Read about them here.

Caution: losing too much sodium or other minerals (e.g., zinc, potassium and magnesium) in the urine can lead to serious new problems.

Chlorthalidone (Hygroton) treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. This medication is also used to treat high blood pressure (hypertension).

How to use :

  • Chlorthalidone taking pillUse Chlorthalidone (Hygroton) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
  • Take it by mouth with food, preferably in the morning.
  • It will increase urination. If you are taking it once a day, you should take it in the morning to prevent it from affecting your sleep.
  • If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Chlorthalidone (Hygroton) .

What to know before using Chlorthalidone (Hygroton) :

If any of the following apply to you, discuss with your doctor before taking Chlorthalidone (Hygroton) :

  • kidneysif you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or non-prescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have gout, liver disease, low blood levels of potassium or sodium, kidney disease, or lupus
  • if you have a history of allergy or bronchial asthma

If you are taking any of the drugs below, the risk of their side effects may be increased by Chlorthalidone (Hygroton)

  • Diazoxide
  • digitalis glycosides (eg, digoxin)
  • ketanserin
  • lithium

Contact your doctor right away if any of these apply to you.

  • allergic to any ingredient in chlorthalidone
  • allergic to any ingredient in thiazides (eg, hydrochlorothiazide) or related diuretics
  • allergic to any ingredient in any sulfonamide-like medicine (eg, sulfisoxazole)
  • or are unable to urinate

Side effects of Chlorthalidone (Hygroton) :

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

  • Constipationdizziness
  • dizziness
  • headache
  • light-headedness (especially when sitting up or standing)
  • low potassium levels
  • Sunburn more easily

Seek medical attention right away if any of these SEVERE side effects occur while taking Chlorthalidone (Hygroton) :

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
  • drowsiness
  • dry mouth
  • impotence
  • inflammation of the pancreas
  • muscle pain or cramps
  • nausea
  • rapid or irregular heartbeat
  • rash or itching
  • restlessness
  • unusual thirst
  • unusual tiredness or weakness
  • vomiting
  • yellowing of the skin or eyes.
  • If your doctor prescribes a potassium supplement, follow the dosing carefully, as too much potassium can lead to hyperkalemia. Do not start taking additional potassium on your own or change your diet to include more potassium without first checking with your doctor. This includes nutritional supplements.
  • You may need lab tests while taking chlorthalidone: including liver function, kidney function, and electrolytes, may be performed while you use chlorthalidone. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Chlorthalidone should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using chlorthalidone while you are pregnant. Chlorthalidone is found in breast milk. Do not breast-feed while taking chlorthalidone.

The information about Chlorthalidone comes from


Chlorthalidone (Hygroton) Natural Alternatives:

Tikva with chocolatedrinkIf you are taking Chlorthalidone (Hygroton) or other diuretic medications, the various ingredients  in Tikva have been proven through either clinical trials or other research to lower your blood pressure naturally by dilating (widening) the arteries. Tikva does not act as a diuretic.
Several of the ingredients in Tikva can also increase circulation, dissolve plaque that is already in the arteries and reduce new plaque from forming. In addition, there are ingredients in Tikva to help reduce stress that often increases blood pressure without all of the side effects.
Read more about the natural ingredients in Tikva on our research and ingredients page, by clicking here.


watermellonVarious herbs, foods and beverages offer a natural diuretic effect; however, they should be used with caution, in the event of unknown medical conditions with fluid retention as a symptom, or due to side effects with other medications. Consult with your physician prior to using natural diuretics.

Cutting back on sodium and exercising more can also help reduce fluid buildup.

Eating more fruits and vegetables that act as diuretics, like watermelon, grapes, berries, celery, asparagus, onions, garlic, and bell peppers, may be another beneficial solution.


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The information provided on this page should not be used to decide whether or not to take Chlorthalidone (Hygroton) or any other medicine. Consult your doctor to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition.

This information about Chlorthalidone (Hygroton) is a brief summary and does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Chlorthalidone (Hygroton).

This information is not specific medical advice and does not replace information you receive from your health care provider. You must speak with your doctor for complete information about the risks and benefits of using Chlorthalidone (Hygroton).