L-Citrulline
|
|
|
Aids in Production of Arginine |
| |
Increases engergy |
|
Detoxify and remove ammonia from liver |
What Is It?
Citrulline is alpha amino gamma ureidovaleric acid. It is formed from ornithine and takes part in the synthesis of urea. It donates one of its nitrogen for the synthesis of urea. Arginine is synthesized from citrulline in presence of aspartic acid, ATP and Mg ++ Citrulline is found in high concentration in the liver. Citrulline is not a component of any major proteins or enzymes.
In the mitochondria, the ‘power house’ of cells, ammonia combines with carbon dioxide and ornithine to form citrulline. Citrulline is then transported out of the mitochondria into the cytoplasm where it is then converted to yet another amino acid called arginine. Thus citrulline is essential to detoxify and remove ammonia from muscle and liver cells.
Citrulline is a non-essential amino acid and plays a role in nitrogen balance and metabolic processes. Although not a component of most proteins in the body, citrulline is found in some specialized proteins in the hair, skin and neural cells. It is primarily synthesized from glutamine in the intestines but is also found naturally in trace amounts in some foods.
Health Vitamins Guide
Click Here to go back to top
Health Benefits
Enhance Arginine Availability
oral citrulline can be used to enhance systemic citrulline and arginine availability, because citrulline is bioavailable and very little citrulline is lost in urine.
AJP - Gastrointestinal and Liver Physiology
Our bodies use citrulline to make yet another amino acid, arginine, which helps cells divide, wounds heal, and ammonia to be removed from the body.
Blood levels of arginine, synthesized in the body from the citrulline provided by the watermelon juice, were 11 percent higher in volunteers tested after three weeks on the three-glasses-a-day regimen (24 ounces), and 18 percent higher following the six-daily-glasses regimen (48 ounces), when compared to levels in samples from volunteers who didn't drink the melon juice.
Now, the scientists want to determine the best way to extract citrulline from watermelon. Preliminary results of medical research—done elsewhere—suggest that arginine might help treat high blood pressure, unhealthy blood sugar levels and vascular disorders associated with sickle-cell disease.
Science Daily
Citrullines other Benefits
-
The amino acid citrulline is required to detoxify the liver from ammonia, which is a waste product of the body from oxidation.
-
Citrulline promotes energy and assists with the immune system. This unusual amino acid is formed in the urea cycle by the addition of carbon dioxide and ammonia to ornithine.
-
It is then combined with aspartic acid to form arginosuccinic acid, which later is metabolized into the amino acid arginine.
-
It helps in the production of energy and thus prevents the muscles from fatigue.
-
It also plays an essential role in maintaining the acid base balance in the body.
Health Vitamins Guide
Click Here to go back to top
|