Indapamide (Lozol)
What You Should Know

Brand Name: Lozol

What is Indapamide (Lozol)?

The Information about Indapamide (Lozol) contained herein is a compilation of materials available from and simplified for the average consumer.

indapamide lozolIndapamide  or brand name Lozol is a diuretic that helps rid your body of salt (sodium) and water. Indapamide (Lozol) works by making your kidneys put more sodium into your urine. The sodium, in turn, takes water with it from your blood. That decreases the amount of fluid flowing through your blood vessels, which reduces pressure on the walls of your arteries.

There are drug free alternatives to lowering your blood pressure that may be effective for you. You can read about them here.

Caution: losing too much sodium or other minerals (e.g., zinc, potassium and magnesium) in the urine can lead to serious new problems.

Indapamide (Lozol) treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. This medication is also used to treat high blood pressure (hypertension).

How to use :

  • Chlorthalidone taking pillUse Indapamide (Lozol) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
  • Take it by mouth with food to avoid an upset stomach, preferably in the morning.
  • Indapamide (Lozol) will increase urination. If you are taking 1 dose of Indapamide (Lozol) daily, take it in the morning to prevent this from affecting your sleep.
  • If you miss a dose of Indapamide (Lozol) and you are taking 1 dose daily, take the missed dose if you remember the same day. Skip the missed dose if you do not remember until the next day. Do not take 2 doses at once.
  • Store Indapamide at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Keep away from heat, moisture, and light. Do not store in the bathroom. Keep Indapamide out of the reach of children and away from pets.

Ask your health care provider any questions you may have about how to use Indapamide (Lozol).

What to know before using Indapamide (Lozol):

Do not use Indapamide (Lozol) if:

  • you are allergic to any ingredient in Indapamide (Lozol) or to a sulfonamide medicine (eg, sulfamethoxazole)
  • you are unable to urinate
  • you are taking ketanserin

If any of the following apply to you, discuss with your doctor before taking Indapamide (Lozol):

  • if you are pregnant, planning to become pregnant, or are breast-feedingcongestive heart failure
  • if you are taking any prescription or non-prescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart problems (eg, irregular heartbeat, heart failure)
  • liver problems (eg, cirrhosis)
  • kidney disease
  • gout
  • lupus
  • problems urinating
  • swelling
  • if you have severe or persistent vomiting
  • low blood levels of sodium or potassium, or if you are on a low-salt (sodium) diet.
  • if you have had a certain neurosurgical procedure (sympathectomy)
  • if you are receiving fluids through a vein (parenteral fluids)

If you are taking any of the drugs below, the risk of their side effects may be dangerously increased by Indapamide (Lozol)

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (ex. ibuprofen)
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril)
  • Diazoxide
  • Adrenocorticotropin hormone (ACTH) or corticosteroids (eg, prednisone)
  • Amantadine
  • Antineoplastic agents (eg, cyclophosphamide)
  • Digitalis glycosides (eg, digoxin)
  • Ketanserin
  • Lithium
  • Any other blood pressure medication

Ask your doctor if Indapamide (Lozol) may interact with any other medications that you take.

Side effects of Indapamide (Lozol):

Seek medical attention right away if any of these severe side effects occur while taking Indapamide (Lozol):

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
  • blurred visionblurred vision
  • chest pain
  • dark urine
  • decreased urination or urination problems
  • dry mouth
  • fainting
  • fast heartbeat
  • fatigue
  • fever
  • chills
  • cough
  • sore throat
  • increased thirst
  • loss of appetite
  • numbness of the hands or feet
  • pale stools
  • red, swollen, blistered, or peeling skin
  • severe or persistent dizziness
  • drowsiness
  • light headed
  • severe stomach pain
  • swelling of the hands, ankles, or feet
  • symptoms of low blood potassium (eg, irregular heartbeat; muscle pain, weakness, or cramping)
  • symptoms of low blood sodium (eg, confusion, mental or mood changes, seizures, sluggishness)
  • unusual bruising or bleeding
  • unusual tiredness or weakness
  • yellowing of the skin or eyes

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

  • Back painvomiting
  • constipation
  • diarrhea
  • dizziness or light headed when siting up or standing
  • drowsiness
  • headache
  • nausea
  • nervousness
  • runny nose
  • trouble sleeping
  • upset stomach
  • vomiting
  • weakness


The information about Indapamide comes from

Indapamide (Lozol) Natural Alternatives:

tikvawithdrinkIf you are taking Indapamide (Lozol) or other diuretic medications, the various ingredients  in Tikva have been proven through either clinical trials or other research to lower your blood pressure naturally by dilating (widening) the arteries. Tikva does not act as a diuretic.
Several of the ingredients in Tikva can also increase circulation, dissolve plaque that is already in the arteries and reduce new plaque from forming. In addition, there are ingredients in Tikva to help reduce stress that often increases blood pressure without all of the side effects.
Read more about the natural ingredients in Tikva on our research and ingredients page, by clicking here.

watermellonVarious herbs, foods and beverages offer a natural diuretic effect; however, they should be used with caution, in the event of unknown medical conditions with fluid retention as a symptom, or due to side effects with other medications. Consult with your physician prior to using natural diuretics.

Cutting back on sodium and exercising more can also help reduce fluid buildup.

Eating more fruits and vegetables that act as diuretics, like watermelon, grapes, berries, celery, asparagus, onions, garlic, and bell peppers, may be another beneficial solution.

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The information provided on this page should not be used to decide whether or not to take Indapamide (Lozol) or any other medicine. Consult your doctor to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition.

This information about Indapamide (Lozol) is a brief summary and does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Indapamide (Lozol).

This information is not specific medical advice and does not replace information you receive from your health care provider. You must speak with your doctor for complete information about the risks and benefits of using Indapamide (Lozol).