What Tikva Users Have To Say


I have been taking these ingredients for over 1 year now.  It has been great!

My blood pressure went from 160/101 to 115/75.  My total cholesterol went from over 300 to 201.  This all happened in less than 6 months after taking these ingredients.  

Carter R.


My husband and I wanted to let you know what our experience with these ingredients has been, even at this early stage. This Wednesday marks 4 weeks on the drink.

Daniel is 42. His health is good except for the high blood pressure. He's been on Lisinopril and Indapam for about two years. He became a living zombie. It was a struggle for him some days to get the dishes washed and unload the dishwasher. He had almost every side effect listed for these drugs. In looking back, we realized that he is someone that is extremely sensitive to medicine and responds very quickly to them (either way).

We received the shipment on Wednesday, March 16th, and he began taking it. His energy began coming back the following Monday, and has remained (and gotten better).

On Friday, April 1 he had to stop taking the diuretic medicine because his blood pressure was dropping too low. Once this diuretic was stopped, everything leveled out within the target range.

He began having another symptom of skin rash/eczema and I got on the Internet to find out more about ACE inhibitors. Once we found out it was based on the venom of a Brazilian pit viper snake, the symptoms he's been experiencing were completely understandable.

He's now cut his ACE inhibitor in half, and is still in the target range on the blood pressure. We feel like that with a bit more time on the formula, he will be off of these medicines.

These ingredients have given me my husband back.

Thank you so much!

Best regards,
Ann and Dan R .


I am 45 years old and have been diagnosed with having high blood pressure (150 over 93). Because of my medical plan changing I have seen several different doctors, over a 2 year period, all are family practitioners. Each doctor prescribed different blood pressure medicine which I took and followed there direction. I saw no difference in my blood pressure. My biggest problem was with the side effects of each drug.

Then my life changed when I started taking these ingredients. I have seen my blood pressure drop to 125 over 79 in 2.5 months. I no longer take blood pressure prescription medication and my doctor considers my blood pressure to be normal, I agree. Thank you.

Brent M.


My mom died of a stroke at age fifty... My oldest brother died of a congenital heart problem at football practice at 16. My dad died at seventy of heart problems after suffering with bad circulation that limited, for many years, his ability to walk.

At age sixty I am 5' 9" and 163 lbs. I had been working out at a gym for six months and had all but eliminated alcohol. At an annual physical in early March, I was disappointed to learn that my blood pressure, for which I had been taking metoprolol, was 168/98.My doctor, an internal medicine guy who was tired of seeing his patients going down with heart attacks and strokes, made it clear that he viewed me as a "walking time bomb." Given the family history that I have to work with, it was impossible to argue and I put up only modest resistance when he prescribed Lipitor. Soon after I began taking these ingredients my daily readings began to go steadily down and the most recent lab results show:

LDL at 72 or one half of what it was a month ago

HDL 49, up 6 from a month ago

Triglycerides 82, down from 102

Blood pressure at 123/68.

My doctor was delighted. Me too. If the trend continues, he has promised to review the need for Lipitor and maybe even metoprolol. I will be one happy man to see those things go.

Regards,
Steve


Two months ago, despite swimming and jogging for an hour each day, my blood pressure was 187 over 98. I freaked. After using these ingredients for just 9 weeks now I am already down to 144/84. I know that it takes most people 3 months to get it down but I am very pleased so far.

Jack O


I have been using these ingredients for 2 1/2 months and my blood pressure has dropped from about 180/100 to an average of 125/80. This decrease occurred without other medication. My doctor wanted to put me on an ace-inhibitor medication but I decided to take these ingredients instead. I'm glad I did.

J Patterson


Hi. This is Heidi. My husband has been taking these ingredients. His blood pressure was 144/83. Not real high, but high enough to become a problem. His blood pressure now is averaging from 125 to 118. Well within normal range. He seems much more relaxed. I am convinced that this is helping him. It is just by a stroke of luck that I found your website. I am going to tell other people with similar conditions.

We are still working on losing the weight, but that takes a little time.

Thank you, and take care,

Heidi D.


In December 2005, during a physical my blood pressure was 149/95. My cholesterol was 267. I was headed for a stroke. My wife's physician had suggested liquid arginine for high blood pressure and she found these ingredients on the internet.

My blood pressure is now a perfect 120/80 and my cholesterol is down to 222 so far. My doctor is so pleased that he decided to keep me OFF the medications.

Thanks,
Rick


My 81 year old mom got her 6 month check up from her doctor today and her blood pressure was 120 over 75, and he said whatever you are doing keep doing it. I asked her did you tell him about the ingredients you are taking. She said nope, she was afraid to, afraid that he would get mad at her….isn’t that something.
 
Well let me back up a little. Back in late October of 2006 my mom was very sick. She could barely stand up without passing out and you could forget going up stairs. We took her to her doctor and he had an ambulance take her right to the hospital with a blood pressure approaching 200 over 120+. So they did the little trick where they go up the leg and found her to be 90% blocked all over. They discussed open heart surgery but were concerned because the veins they would use in her legs were too small. Well she said no, she wanted to wait until after Christmas (in case it was her last) so she could spend it with her grand kids. That is when I put her on these ingredients.
 
Well the doctor’s office called her in January and told her she needed to get the angioplasty done. She said no I feel a whole lot better now with my blood pressure down to around the 140 over 80s range. So they talked her into going back up the leg to take a another look and this time at the very most she was only 40% blocked just in one spot, so they put in a stint (which I don’t think was necessary).
 
Well I just wanted to say thanks for adding a few more years to my mom’s life! I kind of like having her around.
 
Ted



Magnesium (mâg-nç'zç-əm)

Improve Endothelial Dysfunction
Control High Blood Pressure
Improve Angina and Irregular Heartbeat (Arrhythmia)
Improve Diabetes
 
Helps Osteoporosis
 
Decrease Frequency and Severity of Migraine Headaches
 
Relieve PMS (premenstrual syndrome)
Reduce Irritability, Chronic Depression, and Anxiety




What Is It?

Magnesium is the fourth most abundant mineral in the body and is essential to good health. Approximately 50% of total body magnesium is found in bone. The other half is found predominantly inside cells of body tissues and organs. Only 1% of magnesium is found in blood, but the body works very hard to keep blood levels of magnesium constant.

Magnesium is needed for more than 300 biochemical reactions in the body. It helps maintain normal muscle and nerve function, keeps heart rhythm steady, supports a healthy immune system, and keeps bones strong. Magnesium also helps regulate blood sugar levels, promotes normal blood pressure, and is known to be involved in energy metabolism and protein synthesis. There is an increased interest in the role of magnesium in preventing and managing disorders such as hypertension, cardiovascular disease, and diabetes.

Office of Dietary Supplements

Click Here to go back to top

 

Health Benefits

Endothelial dysfunction

Vascular endothelial cells line arterial walls where they are in contact with the blood that flows through the circulatory system. Normally functioning vascular endothelium promotes vasodilation when needed, for example, during exercise, and inhibits the formation of blood clots. In cardiovascular disease, arteries develop atherosclerotic plaque. Atherosclerosis impairs normal endothelial function, increasing the risk of vasoconstriction and clot formation, which may lead to heart attack or stroke. Recent research indicates that pharmacologic doses of oral magnesium may improve endothelial function in individuals with cardiovascular disease. A randomized double-blind , placebo -controlled trial in 50 men and women with stable coronary artery disease found that six months of oral magnesium supplementation (730 mg/day) resulted in a 12% improvement in flow-mediated vasodilation compared to placebo. In other words, the normal dilation response of the brachial (arm) artery to increased blood flow was improved. Magnesium supplementation also resulted in increased exercise tolerance during an exercise stress test compared to placebo. In another study of 42 patients with coronary artery disease who were already taking low-dose aspirin (an inhibitor of platelet aggregation), three months of oral magnesium supplementation (800-1,200 mg/day) resulted in an average 35% reduction in platelet-dependent thrombosis, a measure of the propensity of blood to clot. Additionally, a recent study in 657 women participating in the Nurses' Health Study reported that dietary magnesium intake was inversely associated with E-selectin, a marker of endothelial dysfunction. Cell culture studies have associated low magnesium concentrations with endothelial dysfunction, namely inhibition of endothelial proliferation. Although preliminary, these studies suggest that magnesium may be of benefit in improving endothelial function in individuals with cardiovascular diseases. 

Linus Pauling Institute

Control high blood pressure

Magnesium is one of the body's most important minerals. It is required as a cofactor in hundreds of enzymatic processes within cells. Magnesium is a major factor in relaxing the smooth muscles within the blood vessels, thereby reducing peripheral vascular resistance and blood pressure. In addition, magnesium reduces nerve and muscle excitability, stabilizes cardiac conductivity, and influences neurochemical transmission. Magnesium also affects circulating levels of norepinephrine and the synthesis of serotonin and nitric oxide.

Indeed, because of magnesium's primary role in blood pressure regulation, for decades scientists have called magnesium “nature's calcium channel blocker” because magnesium directly offsets the constriction of blood vessels caused by calcium. Because drug companies cannot make money from a natural substance like magnesium , they have developed a whole group of drugs called calcium antagonists or calcium channel blockers to do what magnesium does.

A 1989 study published in the journal Hypertension found that taking 625 mg of magnesium daily produced significant reductions in blood pressure in 21 subjects. A study published in 1993 in the American Journal of Hypertension found that taking supplemental magnesium reduced average systolic blood pressure from 154 to 146 mm Hg and cut average diastolic blood pressure from 100 to 92 mm Hg. The authors commented: “For the first time in a double-blind, placebo-controlled study, we have demonstrated that oral magnesium results in a significant dose-dependent reduction of systolic and diastolic blood pressure.”

A study published in the International Journal of Cardiology in 1996 found that taking 600 mg of magnesium daily reduced systolic blood pressure by an average of 7.6 mm Hg and diastolic pressure by an average of 3.8 mm Hg. In another double-blind, placebo-controlled study published in the British Journal of Nutrition in 1997, subjects who took 411-548 mg of magnesium daily experienced significant reductions in systolic and diastolic blood pressure.

Life Extension

An observational study examined the effect of various nutritional factors on incidence of high blood pressure in over 30,000 US male health professionals. After four years of follow-up, it was found that a lower risk of hypertension was associated with dietary patterns that provided more magnesium, potassium, and dietary fiber. For 6 years, the Atherosclerosis Risk in Communities (ARIC) Study followed approximately 8,000 men and women who were initially free of hypertension. In this study, the risk of developing hypertension decreased as dietary magnesium intake increased in women, but not in men.

Some observational surveys have associated higher blood levels of magnesium with lower risk of coronary heart disease. In addition, some dietary surveys have suggested that a higher magnesium intake may reduce the risk of having a stroke. There is also evidence that low body stores of magnesium increase the risk of abnormal heart rhythms, which may increase the risk of complications after a heart attack. These studies suggest that consuming recommended amounts of magnesium may be beneficial to the cardiovascular system.

Office of Dietary Supplements

Angina and irregular heartbeat (arrhythmia)

Without adequate levels of magnesium, your heart will suffer; The mineral helps coordinate the activity of the heart muscle as well as the functioning of the nerves that initiate the heartbeat. It also helps keep coronary arteries from spasming, an action that can cause the intense chest pain known as angina. If you have a deficiency of magnesium--often true of those with angina and abnormal heart rhythms--supplements may help. One study of more than 230 people with frequent arrhythmias showed the likelihood of these abnormal rhythms dropped significantly within three weeks after the participants increased the amount of magnesium and potassium in their diets. Several studies have shown administering magnesium intravenously seems to improve arrhythmias. In addition, when given by injection in a hospital setting, magnesium has been found to aid recovery from a heart attack by stabilizing heart rhythm, inhibiting blood clots, and expanding coronary arteries. Some studies even indicate that drinking "hard" water, which is high in magnesium, lowers the risk of death from heart attack.

WholeHealthMD.com

Limit complications of congestive heart failure

Because magnesium can help lower blood pressure and inhibit dangerous arrhythmias, two common complications in those with congestive heart failure, a weakened heart may benefit from extra doses of this mineral.

WholeHealthMD.com

Diabetes

Diabetes is a disease resulting in insufficient production and/or inefficient use of insulin. Insulin is a hormone made by the pancreas. Insulin helps convert sugar and starches in food into energy to sustain life. There are two types of diabetes: type 1 and type 2. Type 1 diabetes is most often diagnosed in children and adolescents, and results from the body's inability to make insulin. Type 2 diabetes, which is sometimes referred to as adult-onset diabetes, is the most common form of diabetes. It is usually seen in adults and is most often associated with an inability to use the insulin made by the pancreas. Obesity is a risk factor for developing type 2 diabetes. In recent years, rates of type 2 diabetes have increased along with the rising rates of obesity.

Magnesium plays an important role in carbohydrate metabolism. It may influence the release and activity of insulin, the hormone that helps control blood glucose (sugar) levels. Low blood levels of magnesium (hypomagnesemia) are frequently seen in individuals with type 2 diabetes. Hypomagnesemia may worsen insulin resistance, a condition that often precedes diabetes, or may be a consequence of insulin resistance. Individuals with insulin resistance do not use insulin efficiently and require greater amounts of insulin to maintain blood sugar within normal levels. The kidneys possibly lose their ability to retain magnesium during periods of severe hyperglycemia (significantly elevated blood glucose). The increased loss of magnesium in urine may then result in lower blood levels of magnesium. In older adults, correcting magnesium depletion may improve insulin response and action.

Several clinical studies have examined the potential benefit of supplemental magnesium on metabolic control of type 2 diabetes. In one such study, 63 subjects with below normal serum magnesium levels received either 2.5 grams of oral magnesium chloride daily "in liquid form" (providing 300 mg elemental magnesium per day) or a placebo. At the end of the 16-week study period, those who received the magnesium supplement had higher blood levels of magnesium and improved metabolic control of diabetes, as suggested by lower Hemoglobin A1C levels, than those who received a placebo. Hemoglobin A1C is a test that measures overall control of blood glucose over the previous 2 to 3 months, and is considered by many doctors to be the single most important blood test for diabetics.

Office of Dietary Supplements

Research also suggests that magnesium supplementation may help treat Insulin resistance and help prevent developing diabetes. Preliminary findings also indicate that having sufficient amounts of magnesium may protect against type 2 diabetes and its complications, such as eye disease. More research on this potentially important role for magnesium in diabetes prevention is needed, however.

WholeHealthMD.com

Magnesium improves insulin sensitivity . Magnesium helps correct impaired insulin sensitivity, the fundamental defect that characterizes pre-diabetes and metabolic syndrome. An intracellular enzyme called tyrosine kinase requires magnesium to allow insulin to exert its blood-sugar-lowering effects. In several studies, daily oral magnesium supplementation substantially improved insulin sensitivity by 10% and reduced blood sugar by 37%.

Life Extension

Magnesium and osteoporosis

Bone health is supported by many factors, most notably calcium and vitamin D. However, some evidence suggests that magnesium deficiency may be an additional risk factor for postmenopausal osteoporosis. This may be due to the fact that magnesium deficiency alters calcium metabolism and the hormones that regulate calcium. Several human studies have suggested that magnesium supplementation may improve bone mineral density. In a study of older adults, a greater magnesium intake maintained bone mineral density to a greater degree than a lower magnesium intake. Diets that provide recommended levels of magnesium are beneficial for bone health, but further investigation on the role of magnesium in bone metabolism and osteoporosis is needed.

Office of Dietary Supplements

 

Migraine headaches

Individuals who suffer from recurrent migraine headaches have lower intracellular magnesium levels (demonstrated in both red blood cells and white blood cells) than individuals who do not experience migraines. Oral magnesium supplementation has been shown to increase intracellular magnesium levels in individuals with migraines, leading to the hypothesis that magnesium supplementation might be helpful in decreasing the frequency and severity of migraine headaches. Two placebo -controlled trials have demonstrated modest decreases in the frequency of migraine headaches after supplementation with 600 mg/day of magnesium. However, another placebo-controlled study found that 485 mg/day of magnesium did not reduce the frequency of migraine headaches. More recently, a placebo-controlled trial in 86 children with frequent migraine headaches found that oral magnesium oxide (9 mg/kg body weight/day) reduced headache frequency over the 16-week intervention.

Linus Pauling Institute

In a study of 81 patients who received 600 mg trimagnesium dicitrate or placebo daily for 12 weeks, those taking magnesium supplementation reported a 41 percent reduction in frequency of migraines and significant improvement in the severity of migraines.

WholeHealthMD.com

Relieve PMS (premenstrual syndrome) discomforts

Because deficiencies in magnesium have been found in many women suffering from PMS, taking magnesium supplements may help this problem. Menstrual cramping, which is caused by hormone like substances called Prostaglandins made by the endometrial cells, may subside with supplemental doses of magnesium and calcium. Both minerals help to lower the production of prostaglandins. Magnesium's muscle-relaxing properties probably have a beneficial effect on cramping of the uterine muscle as well. Taking magnesium also seems to improve symptoms such as mood changes and fluid retention.

WholeHealthMD.com

Reduce emotional irritability in chronic depression, anxiety, and panic disorder

Magnesium and vitamin B6 are needed for the body to produce Serotonin, an important mood-enhancing brain chemical. When depression or a panic disorder is persistent--and especially when the usual drugs have limited effect--supplementing with magnesium and vitamin B6 may provide significant relief. It may take six weeks or more of treatment for effects to be felt. Taking calcium along with magnesium may also lessen an overreaction to stress that some research has linked to anxiety and panic attacks.

WholeHealthMD.com

Click Here to go back to top

The information herein is not intended to replace the medical advice of your physician. You are advised to consult with your physician with regards to matters relating to your health, and in particular regarding matters that may require diagnosis or medical attention. DO NOT stop taking medications without first consulting with your physician. These statements have not been evaluated by the Food and Drug Administration.

Every effort has been made to ensure that the information provided herein is accurate, up-to-date, and complete, but no guarantee is made to that effect. This information has been compiled for use by healthcare practitioners and consumers in the United States. Heart 2 Heart of America does not endorse drugs, diagnose patients or recommend therapy. This informational resource is designed to assist licensed healthcare practitioners in caring for their patients and/ or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. Heart 2 Heart of America does not assume any responsibility for any aspect of healthcare administered with the aid of information Heart 2 Heart of America compiles. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions, check with your doctor, nurse or pharmacist.