What Tikva Users Have To Say


I have been taking these ingredients for over 1 year now.  It has been great!

My blood pressure went from 160/101 to 115/75.  My total cholesterol went from over 300 to 201.  This all happened in less than 6 months after taking these ingredients.  

Carter R.


My husband and I wanted to let you know what our experience with these ingredients has been, even at this early stage. This Wednesday marks 4 weeks on the drink.

Daniel is 42. His health is good except for the high blood pressure. He's been on Lisinopril and Indapam for about two years. He became a living zombie. It was a struggle for him some days to get the dishes washed and unload the dishwasher. He had almost every side effect listed for these drugs. In looking back, we realized that he is someone that is extremely sensitive to medicine and responds very quickly to them (either way).

We received the shipment on Wednesday, March 16th, and he began taking it. His energy began coming back the following Monday, and has remained (and gotten better).

On Friday, April 1 he had to stop taking the diuretic medicine because his blood pressure was dropping too low. Once this diuretic was stopped, everything leveled out within the target range.

He began having another symptom of skin rash/eczema and I got on the Internet to find out more about ACE inhibitors. Once we found out it was based on the venom of a Brazilian pit viper snake, the symptoms he's been experiencing were completely understandable.

He's now cut his ACE inhibitor in half, and is still in the target range on the blood pressure. We feel like that with a bit more time on the formula, he will be off of these medicines.

These ingredients have given me my husband back.

Thank you so much!

Best regards,
Ann and Dan R .


I am 45 years old and have been diagnosed with having high blood pressure (150 over 93). Because of my medical plan changing I have seen several different doctors, over a 2 year period, all are family practitioners. Each doctor prescribed different blood pressure medicine which I took and followed there direction. I saw no difference in my blood pressure. My biggest problem was with the side effects of each drug.

Then my life changed when I started taking these ingredients. I have seen my blood pressure drop to 125 over 79 in 2.5 months. I no longer take blood pressure prescription medication and my doctor considers my blood pressure to be normal, I agree. Thank you.

Brent M.


My mom died of a stroke at age fifty... My oldest brother died of a congenital heart problem at football practice at 16. My dad died at seventy of heart problems after suffering with bad circulation that limited, for many years, his ability to walk.

At age sixty I am 5' 9" and 163 lbs. I had been working out at a gym for six months and had all but eliminated alcohol. At an annual physical in early March, I was disappointed to learn that my blood pressure, for which I had been taking metoprolol, was 168/98.My doctor, an internal medicine guy who was tired of seeing his patients going down with heart attacks and strokes, made it clear that he viewed me as a "walking time bomb." Given the family history that I have to work with, it was impossible to argue and I put up only modest resistance when he prescribed Lipitor. Soon after I began taking these ingredients my daily readings began to go steadily down and the most recent lab results show:

LDL at 72 or one half of what it was a month ago

HDL 49, up 6 from a month ago

Triglycerides 82, down from 102

Blood pressure at 123/68.

My doctor was delighted. Me too. If the trend continues, he has promised to review the need for Lipitor and maybe even metoprolol. I will be one happy man to see those things go.

Regards,
Steve


Two months ago, despite swimming and jogging for an hour each day, my blood pressure was 187 over 98. I freaked. After using these ingredients for just 9 weeks now I am already down to 144/84. I know that it takes most people 3 months to get it down but I am very pleased so far.

Jack O

Vitamin B12
Lower Blood Pressure
  Lowers Homocysteine
Protect Against Alzheimer's and Dementia
Ward Off Depression
Prevent Neural Tube Defects




What Is It?

Vitamin B12 is a water-soluble vitamin. Water-soluble vitamins dissolve in water. After the body uses these vitamins, leftover amounts leave the body through the urine. Typically, water-soluble vitamins can not be stored by the body. Vitamin B12 is special, because the body can store it for years in the liver. Because of this, a vitamin B12 deficiency is very rare.

Vitamin B12, like the other B vitamins, is important for metabolism . It helps in the formation of red blood cells and in the maintenance of the central nervous system .

Medline Plus

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Health Benefits

Heart Disease

Taken as part of a vitamin B-complex supplement, vitamin B6 may help protect against heart disease and a host of other disorders. For example, in concert with folic acid and vitamin B12 , it aids the body in processing homocysteine, an amino acid like compound that, at elevated levels, increases the risk for heart disease and other vascular disorders.

Wholehealthmd.com

The amount of homocysteine in the blood is regulated by at least three vitamins: folate (folic acid), vitamin B12 , and vitamin B6. Analysis of the results of 12 homocysteine-lowering trials showed folic acid supplementation (500mcg - 5 mg/day) had the greatest lowering effect on blood homocysteine levels (25% decrease); co-supplementation with folic acid and vitamin B12 (mean 0.5 mg/day or 500 mcg/day) provided an additional 7% reduction (32% decrease) in blood homocysteine concentrations. The results of a sequential supplementation trial in 53 men and women indicated that after folic acid supplementation, vitamin B12 became the major determinant of plasma homocysteine levels. Some evidence indicates that vitamin B 12 deficiency is a major cause of elevated homocysteine levels in people over the age of 60. Two studies found blood methylmalonic acid (MMA) levels to be elevated in more than 60% of elderly individuals with elevated homocysteine levels. An elevated MMA level in conjunction with elevated homocysteine, in the absence of impaired kidney function, suggests either a vitamin B12 deficiency or a combined B12 and folate deficiency. Thus, it is important to evaluate vitamin B12 status as well as kidney function in older individuals with elevated homocysteine levels prior to initiating homocysteine-lowering therapy.

Linus Pauling Institute

Even moderately elevated levels of homocysteine in the blood have been associated with increased risk for cardiovascular disease, including heart disease and stroke. During protein digestion, amino acids, including methionine, are released. Homocysteine is an intermediate in the metabolism of methionine. Healthy individuals utilize two different pathways to metabolize homocysteine. One pathway converts homocysteine back to methionine and is dependent on folic acid and vitamin B12. The other pathway converts homocysteine to the amino acid cysteine and requires two vitamin B6 (PLP)-dependent enzymes. Thus, the amount of homocysteine in the blood is regulated by at least three vitamins: folic acid, vitamin B12 , and vitamin B6. Several large observational studies have demonstrated an association between low vitamin B6 intake or status with increased blood homocysteine levels and increased risk of cardiovascular diseases. A large prospective study found the risk of heart disease in women who consumed, on average, 4.6 mg of vitamin B 6 daily was only 67% of the risk in women who consumed an average of 1.1 mg daily .

Linus Pauling Institute

Although oral B12 did not reduce homocysteine in every case, when it did, the results were dramatic. Some of the people in the study had homocysteine levels as high as 175 micromoles per liter (the optimal safe range for homocysteine is under 6). In the case of one patient, 2,000 micrograms of oral B12 for four months reduced their homocysteine from 113.4 micromoles per liter to 8.2. Injected B12 also significantly reduced homocysteine - the main difference being that the injected version worked faster.

Interestingly, some of the patients did not respond to supplemental vitamin B12. It was discovered that they were also deficient in folate (folic acid), and until folate was replaced, their homocysteine remained elevated. Vitamin B12 and folate work synergistically in the chemical reactions that recycle homocysteine back to methionine in the methylation cycle.

Life Extension

 

Alzheimer's and Dementia

B12-deficiency can cause a dementia that looks exactly like Alzheimer's disease. And the connection between Alzheimer's disease itself is characterized by brain deficiencies of both vitamin B12 and the methylating factor, S-adenosylmethionine (SAMe). A new study from Germany correlates B12 deficiency in Alzheimer's patients with two personality changes—irritability and disturbed behavior. n B12 deficiency and mental illness has been documented repeatedly. According to the latest research, as much as 30% of hospitalized mental patients may be deficient in the vitamin. And what's disturbing is that studies repeatedly show that the deficiency is frequently missed by standard blood tests. For example, a recent study from Germany shows that out of 67 hemodialysis patients who were B12-deficient by the measurement of methylmalonic acid (it goes up when B12 goes down), only two of them were deficient by a standard blood test. Looking at the data, one can't help but wonder how many people with B12 deficiency get treated for mental illness when what they should get is a vitamin!

Life Extension

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Depression

Observational studies have found as many as 30% of patients hospitalized for depression are deficient in vitamin B12. A cross-sectional study of 700 community-living, physically disabled women over the age of 65 found that vitamin B12 deficient women were twice as likely to be severely depressed as non-deficient women. A population-based study in 3,884 elderly men and women with depressive disorders found that those with vitamin B12 deficiency were almost 70% more likely to experience depression than those with normal vitamin B 12 status. The reasons for the relationship between vitamin B12 deficiency and depression are not clear but may involve S-adenosylmethionine (SAMe). Vitamin B12 and folate are required for the synthesis of SAMe, a methyl group donor essential for the metabolism of neurotransmitters whose bioavailability has been related to depression. This hypothesis is supported by several studies that have shown supplementation with SAMe improves depressive symptoms. Because few studies have examined the relationship of vitamin B12 status and the development of depression over time, it cannot yet be determined if vitamin B12 deficiency plays a causal role in depression. However, due to the high prevalence of vitamin B12 deficiency in older individuals, it may be beneficial to screen for vitamin B12 deficiency as part of a medical evaluation for depression.

Linus Pauling Institute

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Neural tube defects

Neural tube defects (NTD) may result in anencephaly or spina bifida , devastating and sometimes fatal birth defects. The defects occur between the 21st and 27th days after conception, a time when many women do not realize they are pregnant. Randomized controlled trials have demonstrated 60% to 100% reductions in NTD cases when women consumed folic acid supplements in addition to a varied diet during the month before and the month after conception. Increasing evidence indicates that the homocysteine -lowering effect of folic acid plays a critical role in lowering the risk of NTD. Homocysteine may accumulate in the blood when there is inadequate folate and/or vitamin B12 for effective functioning of the methionine synthase enzyme . Decreased vitamin B12 levels in the blood and amniotic fluid of pregnant women have been associated with an increased risk of NTD, suggesting that adequate vitamin B12 intake in addition to folic acid may be beneficial in the prevention of NTD. 

Linus Pauling Institute

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The information herein is not intended to replace the medical advice of your physician. You are advised to consult with your physician with regards to matters relating to your health, and in particular regarding matters that may require diagnosis or medical attention. DO NOT stop taking medications without first consulting with your physician. These statements have not been evaluated by the Food and Drug Administration.

Every effort has been made to ensure that the information provided herein is accurate, up-to-date, and complete, but no guarantee is made to that effect. This information has been compiled for use by healthcare practitioners and consumers in the United States. Heart 2 Heart of America does not endorse drugs, diagnose patients or recommend therapy. This informational resource is designed to assist licensed healthcare practitioners in caring for their patients and/ or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. Heart 2 Heart of America does not assume any responsibility for any aspect of healthcare administered with the aid of information Heart 2 Heart of America compiles. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions, check with your doctor, nurse or pharmacist.